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By contrast, X(PC) selectively cleaved the procaspase-1 substrate with no activity on VAMP1 (Extended Data Fig
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The mitochondrial chaperone TRAP1 promotes neoplastic growth by inhibiting succinate dehydrogenase
Nevertheless, the kinetic data for our mutants and rate constants for ScGrx7 and PfGrx between 10 5 10 6 M 1 s 1 are too slow for a diffusion-controlled reaction and point towards important short-lived enzymesubstrate interactions and rate-limiting re-orientations of the substrate at the enzyme surface
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