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So far, clinical evidence for GLP-1s in Parkinsons Disease has been disappointing
Although the pathophysiological processes underlying the cardiovascular disease may improve with weight loss, weight loss alone is insufficient to fully account for the observed cardiovascular improvements
The study provides a detailed mechanistic insight into the interplay between metabolic reprogramming, protein stability, and drug response in the context of obesity and cancer
doi:10.1073/pnas.97.16.8841
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