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If the patient achieves clinically meaningful weight reduction with obesity medications and if the clinician and patient feel that the medication is helping to avoid weight regain, then a weight reduction plateau should not be considered a point where medication should be discontinued, but rather the medication should be continued for weight reduction maintenance
The efficacy and safety of oral semaglutide for glycaemic management in adults with type 2 diabetes compared to subcutaneous semaglutide, placebo, and other GLP-1 RA comparators: a systematic review and network meta-analysis
PlexusDx's dual-compound GLP-Squared Injection ($289/mo) combines semaglutide with tirzepatide, activating both GLP-1 and GIP pathways
And even though my personal recommendation is to avoid them as much as possible, there are situations in which it may make sense to use them temporarily
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