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Gelfand ST et al
These metabolic effects occur through the growth hormone/IGF-1 axis, which plays a central role in regulating lipid metabolism and energy homeostasis
In adipocyte models, both primary cultures and immortalised lines document enhanced lipolysis and induction of thermogenic gene expression including UCP1, PGC-1, and CIDEA, markers of brown adipose tissue activation
But at higher concentrations like 20mg/mL, 1 unit of dead space equals 200mcg, and 5 draws waste 1,000mcg (1mg), which is 5% of a 20mg vial
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