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In 2019, liver-expressed antimicrobial peptide (LEAP2), initially discovered as an antimicrobial peptide produced in the liver, was identified to be upregulated in the stomach of diet-induced obese mice after vertical sleeve gastrectomy

Unlike DAC-modified CJC-1295, CJC-1295 No DAC was developed to produce a more physiologic, short-duration stimulation of the GHRH receptor , making it well suited for studies focused on natural pulsatile GH release rather than prolonged receptor activation

Salanitro M et al