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4030-A COMPARISON OF FIRST-LINE SYSTEMIC THERAPIES FOR ADVANCED HEPATOCELLULAR CARCINOMA: A SYSTEMATIC REVIEW AND NETWORK META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS Moon Haeng Hur 1 , Youngsu Park 1 , Yunmi Ko 1 , Hyunjae Shin 1 , Jeayeon Park 1 , Ju Yeon Kim 1 , Yun Bin Lee 1 , Su Jong Yu 1 , Yoon Jun Kim 2 , Jung-Hwan Yoon 1 and Jeong-Hoon Lee 3 , (1)Seoul National University College of Medicine, (2)Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, South Korea, (3)Seoul National University College of Medicine, Seoul, South Korea Background : Recently, several novel systemic therapies and their combinations have shown favorable outcomes in patients with advanced hepatocellular carcinoma (HCC)
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however, these outcomes remain confined to preclinical research and require further investigation in human studies
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