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Monitor renal function in patients reporting any adverse effect that could lead to volume depletion, especially when initiating semaglutide or escalating dosage
Aim for 1 gram per pound of body weight as a minimum, with 1.2-1.5 grams being preferable during active muscle-building phases
In human adipocytes, tirzepatide exposure results in an increase in both mRNA expression and LPL activity, as well as increased fatty acid uptake into adipocytes
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