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When lab tests really matter There are situations where lab tests move from nice to have into very important. Here are some of the big ones
see Genetics section) Glyphosate (disrupts folate synthesis by gut bacteria, chelates manganese and cobalt) Heavy metals (mercury, lead, arsenic, cadmium all impair methyltransferase enzymes and deplete glutathione, increasing methylation demand) R High-dose niacin (nicotinic acid) (niacin is methylated for excretion, consuming SAM-e and depleting the methyl pool) R Mycotoxin exposure (mycotoxins deplete glutathione and increase methylation demand for detoxification) Nitrous oxide exposure (irreversibly oxidizes the cobalt in methylcobalamin, inactivating methionine synthase
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