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It would be nice to see how much of these data would apply for ultrapid insulin lispro and fast-acting insulin aspart that have in the SPC that it should be administered immediately (2 minutes) before meal or up to 20 minutes after Very interesting data

456 The I-SPY 2 umbrella trial precisely matches multiple novel agents or combination therapies to breast cancer molecular subtypes, enabling rapid assessment of early efficacy signals and adaptive optimization, thereby accelerating the development of precision treatments for high-risk breast cancer patients (NCT01042379)

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doi: 10.4049/jimmunol.0803978 128 VerduraS.CuysE.Martin-CastilloB.MenendezJ