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If, after about 3-4 months, you fall behind your expected weight loss (for example, less than half the predicted loss at this point), it may be time to discuss GLP-1 therapy with your medical team

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At the end of the 12 week experimental treatment period the research team reported that in comparison to the placebo, the patients receiving doses of semaglutide ranging from 0.4-1.6 experienced a greater reduction in levels of fasting plasma glucose

GLP-1 microdosing uses sub-therapeutic doses (0.05-0.25mg semaglutide weekly vs standard 0.25-2.4mg) to minimize gastrointestinal side effects while achieving mild appetite suppression