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Overcorrection can make the face look puffy and distorted from the rest of the body

At baseline, mean age and the proportion of subjects with heart failure and prior CV events were higher, and mean eGFR was lower, in the SUSTAIN 6, PIONEER 5 and PIONEER 6 trials than in the other trials

9 A large meta-analysis of randomised controlled trials published in 2024 found no significant overall association between GLP-1 medications and psychiatric disorders, but the authors noted that ongoing monitoring is advisable

Phaseolamin treatment prevents oxidative stress and collagen deposition in the hearts of streptozotocin-induced diabetic rats