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Given that obesity is a major modifiable risk factor for OSAS, and that the pathogenesis of OSAS involves metabolic dysregulation, systemic inflammation, and abnormal adipose tissue distribution, tirzepatide may offer multidimensional therapeutic benefits in this context (26)
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Compounded formulations permit rapid dosing customization and may align with patients who benefit from stepwise, microdefocused escalationparticularly relevant when genetic predisposition testing suggests variable GLP-1 receptor sensitivity
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