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The proportion of HIF1a + Sox2 + pluripotent NSCs was unchanged by IH (Supplemental Figure S2) in the SGZ, but the proportion of HIF1a + Tbr2 + co-labeled INPs increased following IH (Fig
That makes it a hormone-like molecule akin to insulin (51 amino acids) or the popular weight-loss drugs Ozempic or Wegovy (30 to 31 amino acids)
It also increases the production of stem cells and supports bone repair, suggesting systemic regenerative activity beyond dermatological applications
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