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Pathak treated an atherosclerotic mouse model with the mechanism-based choline TMA lyase inhibitor IMC, a drug similar to DMB, which can prevent the diet-driven accumulation of cholesterol and change the expression of hepatic genes essential for bile acid feedback regulation (49)
10.1161/ATVBAHA.108.174359 Arterioscler Thromb Vasc Biol
Emerging clinical observations in humans suggest that GLP-1 medications may help address underlying inflammatory processes in conditions like rheumatoid arthritis, though more research is needed in this area
Kamran Zamanian, Ph.D., is CEO and founding partner of iData Research
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