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Its efficacy, coupled with its relatively favorable safety profile, positions Semaglutide as a transformative intervention in the fight against obesity-related complications

It is what scientists call a dual GIP and GLP-1 receptor agonist , meaning it activates two different hormone pathways simultaneously: GLP-1 (glucagon-like peptide-1): A gut hormone that reduces appetite, slows gastric emptying (so food stays in your stomach longer and you feel full for longer), and helps regulate blood sugar levels

Additionally, tirzepatide resulted in greater reductions in body weight compared to semaglutide, with estimated treatment differences of 1.9 kg (with 5 mg), 3.6 kg (with 10 mg), and 5.5 kg (with 15 mg)

Symptoms may be stronger when used together during the first few weeks