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Among 502 adults with type 2 diabetes and history of suicidal ideation, a lower risk for recurrent suicidal ideation was observed for the semaglutide group compared with those taking a non-GLP-1 medication (HR = 0.51
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This extensive anatomical integration results in substantial overlap between GLP-1 signaling pathways and the mesolimbic dopamine system, which is central to reward-related behaviors
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