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The most common side effects reported in trials include: Digestive issues Nausea (the most frequently reported side effect) Vomiting Diarrhoea Constipation Stomach pain or discomfort Loss of appetite Other reported effects Fatigue or tiredness Injection site reactions (redness, swelling, or irritation) Most side effects tend to be worse when starting the medication or increasing the dose, and often improve as your body adjusts
We can also recommend supportive treatments to help you maintain muscle mass, energy, and long-term health
In comparison, humans have a few GLP-1 receptors in thyroid C-cells, and GLP-1 receptor agonists like semaglutide do not activate calcitonin release or cause thyroid cancer
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