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Triple hormone receptor agonist retatrutide for metabolic dysfunction-associated steatotic liver disease: a randomized phase 2a trial Phase 2a liver-disease trial that adds human metabolic and safety context
Methods Study design This prospective, non-randomised, open-label cohort study with two active medication arms (semaglutide and metformin), was conducted between September 2021 (first patient, first visit) and March 2024 (last patient, last visit) at Mondriaan, a mental health care institution in the Netherlands
This delay in gastric emptying is also associated with increased satiety and reduced appetite, contributing to weight management
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