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Elevated homocysteine and methylmalonic acid (MMA) are biomarkers of functional B12 insufficiency
Learn more about symptoms of a B12 deficiency on the NHS website
Furthermore, the detection of AOD9604 abuse in athletes requires a solid-phase extraction method, which has been validated in urine with a limit of detection of 50 pg/mL
The 2024 NICE guideline on B12 deficiency in over-16s is built around identifying and treating the cause, not just topping up the number
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