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Originally developed for diabetes and weight loss, GLP-1 medications may help quiet the brains reward circuitry, muting the intense craving signals associated with Substance Use Disorders

Injections bypass those issues

I think the kidney data is inherently striking and valuable, but it also provides insight into what might be happening in other organs where the endothelium is really important in controlling organ function, like the heart. Another observation has been a significant reduction in the amount of fat around the kidneys, with a striking three to five times as much organ fat loss as total body weight loss

The research was published Monday in The Lancet Diabetes & Endocrinology