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The inhibition of complex I activity can further promote the abnormal accumulation of -syn, creating a vicious cycle (Betarbet et al., 2000)

Alternation%= (Number of spontaneous alternations)/(total number of arm entries-2) 100, where one alternation refers to a sequence of three different arms

How Collagen Production Declines with Age Collagen is vital for keeping skin youthful, strong, and robust, yet its production gradually falls with age