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The diagnosis is established by demonstrating abnormally low plasma free carnitine concentrations, reduced carnitine transport of fibroblasts from skin biopsy, and molecular analysis of the gene coding for OCTN2 (33, 34)
Moreover, the ability of DEM to deplete mucosal GSH stores in the absence of damage contrasts with the outcome described with other thiol depleting agents, including N-ethylmaleimide or iodoacetamide
Sweeney, C
Its much better to aliquot your reconstituted solution into smaller, single-use portions before initial freezing or refrigeration, to avoid repeated cycles
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