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Disruption of synaptic connectivity and impaired neuronal signaling are early signs of these diseases, and this could be due to defective processing by synaptic mitochondria, which supply the ATP needed as a source of energy for these functions (Petersen et al., 2019)
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"The freezing step in lyophilization: physico-chemical fundamentals, freezing methods, and consequences on process performance and quality attributes of biopharmaceuticals." European Journal of Pharmaceutics and Biopharmaceutics
A 10-week MeDi intervention in World Trade Center responders with PTSD significantly reduced inflammatory markers such as CRP and lessened PTSD symptom severity compared to standard nutritional advice (Arcan et al., 2024)
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