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The functional consequence in animal models is synergistic rather than additive GH output: GHRH-R priming increases the pool of releasable GH vesicles, and GHS-R1a co-stimulation then drives a larger amplitude pulse than either receptor produces alone
GHK-Cu is a naturally occurring copper-binding peptide investigated for collagen synthesis, extracellular matrix regulation, tissue remodeling, and cellular communication
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