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and it is this feedback loop that we refer to as the research flywheel
SGLT2 inhibitors may improve metabolic profiles in selected non-pregnant patients, but any such use must remain strictly outside pregnancy, under reliable contraception, and with guideline-consistent discontinuation before conception attempts because of urogenital adverse effects and contraindications during pregnancy (155, 156)
doi: 10.1016/s0027-5107(02)00323-8 120 KieferD.PantusoT
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