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The GSH conjugate formation with APAP mitigates the saturation and exhaustion of sulfation and glucuronidation pathways following accumulation of the metabolite, which would otherwise lead to mitochondrial disruption and cellular death 10,58

Eltayeb AE, Kawano N, Badawi GH et al (2007) Overexpression of monodehydroascorbate reductase in transgenic tobacco confers enhanced tolerance to ozone, salt and polyethylene glycol stresses

Cell Mol Biol (noisy-Le-Grand) 62:110 Baron M, Davies S, Alexander L, Snellgrove D, Sloman K (2008) The effect of dietary pigments on the coloration and behaviour of flame-red dwarf gourami, Colisa lalia

Vitamine D : aprs avoir t synthtis partir du calcifediol dans le rein, le calcitriol (mtabolite actif de la vitamine D) permet daugmenter le taux de GSH dans le cerveau et damliorer son action antioxydante au niveau neuronal