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Lipopolysaccharide causes an increase in intestinal tight junction permeability in vitro and in vivo by inducing enterocyte membrane expression and localization of TLR-4 and CD14
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More -- and better -- research is required Clearly more research is needed, but the implications of an orally bioavailable version are exciting and we hope someone can nail it someday soon
At the same time, some evidence suggests that certain GLP-1 drugsespecially semaglutidemay be associated with temporary worsening of diabetic retinopathy in patients who already have retinal disease, particularly when glucose improves quickly
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