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Inhibition of sarcolemmal FAT/CD36 by sulfo-N-succinimidyl oleate rapidly corrects metabolism and restores function in the diabetic heart following hypoxia/reoxygenation

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In the ATTAIN-2 trial in patients with diabetes, discontinuation rates due to adverse events were 6.1-9.9% for orforglipron versus 4.1% for placebo