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Researchers, driven by the quest for small, selective, and membrane-permeable NNMT inhibitors, unearthed the potency of 5-Amino 1MQ
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Antiapoptotic proteins, such as an inhibitor of apoptosis 2 (IAP-2), could be induced whereas the proapoptotic protein Bax could be downregulated in an HIF-1-dependent manner [86]
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