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References Guangyan, Y

Despite these advances, challenges persist, including cytotoxicity, potential microbiome disruptions, and regulatory gaps, demanding biocompatible, scalable innovations like good manufacturing practices-compliant processes and longitudinal safety assessments

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For example, advancing clinical trials of combination therapeutic strategies utilizing EZH2 inhibitors and ferroptosis inducers to validate their synergistic efficacy in cancer treatment, or developing lipid metabolism-based biomarkers e.g., SCD1 expression level for identifying EZH2 inhibitor-sensitive patient populations