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Topical NSAIDs such as ibuprofen gel or diclofenac gel offer localised pain relief for musculoskeletal conditions with minimal systemic absorption, significantly reducing gastrointestinal and cardiovascular risks compared to oral NSAIDs
Lancet Diabetes Endocrinol 5(5):341354 Sorli C, Harashima SI, Tsoukas GM, Unger J, Karsbl JD, Hansen T, Bain SC (2017) Efficacy and safety of once-weekly semaglutide monotherapy versus placebo in patients with type 2 diabetes (SUSTAIN 1): a double-blind, randomised, placebo-controlled, parallel-group, multinational, multicentre phase 3a trial
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