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This activity mediates the differentiation of CD4 + T cells into Th1 and Th17 subtypes, promoting the production of inflammatory factors such as IFN- and IL-17, and shifting their metabolic profile from oxidative phosphorylation to glycolysis [392]

Stremming J, White A, Donthi A, Batt DG, Hetrick B, Chang EI, Wesolowski SR, Seefeldt MB, McCurdy CE, Rozance PJ and Brown LD (2022) Sheep recombinant IGF-1 promotes organ-specific growth in fetal sheep

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