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also evaluated the effect of incretin-based therapy (either GLP-1RAs or DPP-4i) on atherosclerotic plaques obtained from 52 patients with T2DM (of whom 24 were treated with GLP-1RAs or DPP-4i for a mean duration of 26 months) and 30 non-diabetic patients undergoing carotid endarterectomy [58]
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We do not start at a high dose as you could have an increased risk of side effects such as nausea, diarrhea, constipation, and abdominal pain
[148] have highlighted the neuropsychiatric dimensions of GLP-1 RAs, including their potential relevance for relapse vulnerability and cognitive-affective regulation after pharmacotherapy discontinuation
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