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Beyond these canonical targets, v3 integrin overexpression on tumor neo-vasculature and invasive cancer cells enables cRGD peptide-mediated dual targeting of angiogenesis and tumor survival, while nucleolin, aberrantly surface-displayed in proliferating breast cancer cells, offers aptamer-based (AS1411) recognition independent of traditional receptor-ligand paradigms [127]

The most effective approach often involves using a liposomal delivery system, which helps protect the nutrient through the digestive tract for better cellular uptake

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Potential Benefits (preclinical) Fat metabolism: Animal models report reductions in fat mass while lean muscle is preserved [5] [6]