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Abstract Class B1 G protein-coupled receptors (GPCRs) are important regulators of many physiological functions such as glucose homeostasis, which is mainly mediated by three peptide hormones, i.e., glucagon-like peptide-1 (GLP-1), glucagon (GCG), and glucose-dependent insulinotropic polypeptide (GIP)
OZEMPIC (semaglutide) prescribing information
It is important to note that GLP-1 receptor agonists should be used with caution in patients with a history of pancreatitis, and treatment should be discontinued if pancreatitis is suspected, as stated in the MHRA SmPC for Ozempic
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