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This is speculative but mechanistically plausible
These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione
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What does justify paying more: methylcobalamin over cyanocobalamin if you have confirmed MTHFR variants, higher methionine concentrations if baseline homocysteine is elevated, and the addition of L-carnitine if you have documented mitochondrial inefficiency or are combining Lipo C with a ketogenic protocol that depletes endogenous carnitine
