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found that intracerebroventricular injection of recombinant FGF-21 protein promoted hypothalamic corticotropin-releasing hormone expression and activated the hypothalamic-pituitary-adrenal axis in mice, which rebounded plasma corticosterone levels to 85% of those of the wild-type and reversed hepatic glucose allosteric defects [12]
Furthermore, a dual luciferase reporter system assay demonstrated that the luciferase activity of GGCT-3 untranslated region (UTR) (wild-type) decreased after transfection with miR-29b-3p mimics, while the luciferase activity of GGCT-3 mUTR (mut) did not show significant changes in MHCC97H and LNCaP cells (Fig
Mechanisms of discrimination between cobalamins and their natural analogues during their binding to the specific B12-transporting proteins
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