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Nirmatrelvir had a median EC50 value of 88 nM (range: 39-146 nM) against the Omicron sub-variants, reflecting EC50 value fold changes 1.8 relative to the USA-WA1/2020 isolate
It also stimulates acetyl-CoA carboxylase, causing the conversion of acetyl-CoA to malonyl-CoA, and blocking fatty acid transport into the mitochondria
Saumoy, M
Now, a new study published in the journal For this study, researchers analyzed blood and joint fluid samples from participants of the Inflammation in Arthritis (INART) biobank at Aarhus University Hospital in Denmark
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