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In preclinical models, chimeric antigen receptor (CAR)-macrophages (CAR-M) targeting the urokinase plasminogen activator receptor (uPAR), a cell-surface receptor upregulated in HSCs in cirrhotic human livers, demonstrated efficacy in reducing liver fibrosis (180)

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Repeated Sulforaphane treatment reverses depressive-like behavior and exerts antioxidant effects in the olfactory bulbectomy model in mice (2024) 17:762