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These reflect different products Vyleesi is FDA-approved

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The Faculty of Sexual and Reproductive Healthcare (FSRH) recommends that if you start tirzepatide or have a dose change, you should use an additional method of contraception such as condoms, or switch to a non-oral method (like the implant, injection, coil, or patch) for four weeks afterwards

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Case series are weaker evidence than randomized trials, so the article treats these as observations rather than expected results

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It could be dose

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