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The mechanisms underlying the association between adolescent cannabis use and risk of psychotic and cognitive symptoms later in life have been explored in various animal models using exposure to escalating doses of -9-tetrahydrocannabinol (THC), the primary psychoactive compound in cannabis

Monitoring Response Patients or research participants typically notice: Appetite suppression within the first 12 weeks Early satiety and slower gastric emptying by weeks 34 Weight loss trends becoming evident by week 8 Continued improvements in glucose metabolism when paired with semaglutide or tirzepatide Side Effects and Considerations Common side effects include: Nausea Mild gastrointestinal discomfort Constipation Injection site reactions These effects are generally transient and dose-dependent, which is why titration is important

The examples cited herein are based on public information and we make no representations regarding their accuracy or usefulness as precedent

doi: 10.1186/s12864-017-4051-5 99 PateR