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Importantly, 5MQ was found to effectively inhibit HeLa cell proliferation without apparently affecting normal HEK-293 cell proliferation suggesting selectivity for cancer cell biology contexts
PubMed record Malinda KM, et al
Revolutionary NNMT Inhibition Mechanism 5-Amino-1MQ functions as a potent selective inhibitor of nicotinamide N-methyltransferase with IC = 1M, preventing the enzyme from converting nicotinamide to 1-methylnicotinamide
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