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Tirzepatide is a first-of-its-kind dual-action peptide that activates both GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) receptors
Recent studies reported that GLP-1R agonists, such as Val 8 -GLP-1(7-36), exendin-4 and liraglutide, attenuated A 1-42 -induced calcium overload by regulating intracellular calcium homeostasis in cortical or hippocampal pyramidal cells (173, 205, 206)
Assignment of patients into control or intervention groups was random block
Sharon, D
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