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The Gut-Brain Axis and the Vagus Nerve The GLP-1 produced in the intestines after a meal also plays a role in suppressing eating, likely through different circuits than those GLP-1-expressing neurons found in the brain stem
In fact, the SCFAs Acetate, Propionate and Butyrate are the principal luminal anions in humans and other mammalian's colon (309, 392), with some inter-species variability
Neither compound is orally bioavailable in these formulations
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