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NICE guidance (NG28) specifies that GLP-1 receptor agonists should be assessed at 6 months to determine whether treatment should continue, based on specific response criteria

3 Efficacy of various treatments

For example, it is unknown what differences between the baseline characteristics of patients in the clinical trials and those of the Danish population who would begin treatment with the trial medications would be, nor what differences this might have on average efficacy of treatments amongst patients being treated in Denmark (e.g., average reductions of % HbA1c)

Clinicians consider medical history, prior medication response, side-effect risk, and lifestyle factors