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Lipid peroxides could be a part of the cytotoxic mechanism leading to the endothelial injury and elevated blood pressure
When ferroptosis occurs, there is an excessive amount of free Fe 2+ in the cell, and the extremely strong oxidation of Fe 2+ could cause the Fenton reaction or Haber Weiss reaction with H 2 O 2 , thus generating hydroxyl radicals (OH ) and peroxides, which can lead to lipid peroxidation, damage the cell membrane and organelle membranes and lead to cell death
The safety of GHK-Cu during pregnancy and breastfeeding has not been established due to limited data
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