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Beta cell senescence and dedifferentiation Beta cell dysfunction in diabetes may also be attributable to the accumulation of senescent, dedifferentiated and transdifferentiated cells
DOI: 10.1038/243353a0
Because Dihexa activates HGF/c-Met signaling , and this pathway is also involved in some types of tumor progression, caution is advised in: Patients with active cancers History of certain malignancies No human data confirms a cancer risk, but Dihexa is best avoided in patients with cancer unless under strict clinical supervision
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