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Healthcare professionals should: Advise patients about the lack of evidence supporting HCG Explain the risks of severe caloric restriction Discourage combining unlicensed treatments with prescribed medications Offer evidence-based alternatives within NHS weight management services Professional responsibility : Prescribers have a duty to follow GMC guidance on prescribing unlicensed medicines, which requires clear justification and informed consent

Notably, the highest dose tested (54 mg) showed increased gastrointestinal event frequency compared to lower doses, suggesting a dose-relationship for this effect category

Once bacteria are in the vial, they will proliferate, especially if there's no bacteriostatic agent present

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