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GLP-1 medications include semaglutide, dulaglutide, and liraglutide, used for type 2 diabetes and weight management Common gastrointestinal effects (nausea, vomiting, diarrhoea) can lead to fluid loss and electrolyte depletion affecting muscle function Maintaining adequate hydration (1.52 litres daily) and dietary electrolyte intake may help prevent cramping Concurrent medications such as diuretics, SGLT2 inhibitors, and statins may contribute to muscle-related symptoms Persistent, severe, or frequent cramps warrant medical review to assess electrolytes, renal function, and exclude other causes Table of Contents What Are GLP-1 Medications and How Do They Work
The Food Foundation says this is especially worrying as most people regain weight after stopping treatment, making early wraparound support crucial for longterm success
The peptide reduces pro-inflammatory cytokines including TNF-alpha, IL-1beta, and IL-6, and inhibits M1 macrophage activation
It supports tissue repair, reduce inflammation, and promote overall resiliencehelping your body recover faster, move better, and stay stronger
