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Studies show that around 37% of patients discontinue GLP-1 medications within a year due to side effects, with the rate rising to 50% for patients with obesity but not diabetes
Across GLP-1 trials, about 60% of lost weight returns within a year and about 75% over the longer regain curve. Continued treatment has stronger evidence than complete withdrawal
When choosing any skin care product, quality and transparency matter
Those drugs have different molecular structures than orforglipron, Wharton says, which could explain why orforglipron didnt cause the same trouble
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